ATX-0126 is a biodegradable ionizable lipid with improved in vivo activities for siRNA delivery via lipid nanoparticles (LNP). The physicochemical parameters of ATX-0126: pKa 6.316, lipophilicity cLogD 14.03, nanoparticle size 82 nm. The in vivo factor VII knockdown efficiency of ATX-0126 is 97% (0.03mg/kg in mice, i.v.).
Product No: N-1100
N-1100
ATX-0126 (ATX100)
ATX-0126 is a biodegradable ionizable lipid with improved in vivo activities for siRNA delivery via lipid nanoparticles (LNP). [Read More...]
