ATX-0114 (pKa 6.69) is a novel ionizable lipid used in the formation of lipid nanoparticles for RNA delivery. ATX-0114 demonstrated 90% knockdown of Factor VII in an in vivo siRNA assay.
ATX-0114
ATX-0114
ATX-0114 (pKa 6.69) is a novel ionizable lipid used in the formation of lipid nanoparticles for RNA delivery. ATX-0114 demonstrated 90% knockdown of Factor VII in an in vivo siRNA assay.
| Molecular Formula | C37H70N2O5S |
|---|---|
| Molecular Weight (g/mol) | 655.04 |
| CAS Number | 2230647-30-8 |
| Storage | -20 °C |
| Synonyms | Lipid 2,2(8,8) 4C CH3 |
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