AP 811 (NPR-C receptor ligand)

CAS Number: 124833-45-0
Molecular Weight: 914.51
Salt Form: TFA
Purity: >95%
Sequence (3-letter): 2-Naphthoyl-4-Aminophenylacetic acid-Arg-Ile-Asp-Arg-(S)-(-)-2-methylbutamide
Sequence (1-letter): (2-Naphthoyl-4-Aminophenylacetic acid)RIDR((S)-(-)-2-methylbutamide)
Storage: -20 °C or below

AP 811 is a high affinity antagonist of the Natriuretic peptide receptor C (NRP3). It is approximately 20,000 fold more selective for NRP3 than NRP1 and inhibits activity of the Na⁺/K⁺ pump.