CAS Number: 219137-85-6
Molecular Weight: 719.24
Salt Form: N/A
Sequence (3-letter): Ac-Tyr-Val-Ala-Asp-AFC
Sequence (1-letter): Ac-YVAD-AFC
Storage: -20 °C or below
Solubility: DMSO, 10 mg/mL
Ac-YVAD-AFC is a fluorogenic substrate for caspase-1 and caspase-4. Reactions are monitored by measuring an increase in fluorescence signal due to AFC cleavage. The excitation and emission maxima for AFC are 400 nm and 505 nm, respectively.
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