CAS Number: 184179-08-6
Molecular Weight: 502.19
Salt Form: N/A
Sequence (3-letter): Ac-Asp-Glu-Val-Asp-CHO
Sequence (1-letter): Ac-DEVD-CHO
Storage: -20 °C or below
Solubility: 13.7 mg/ml in DMSO
Caspase-3 (Apopain) is commonly activated by numerous death signals and cleaves a variety of important cellular proteins and is essential for brain development. Ac-DEVD-CHO is a potent, reversible inhibitor of caspase-3 (Ki < 1nM for purified caspase-3) and also inhibits caspase-7 (Ki = 1.6 nM) as well as other caspases to a lesser extent.
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