2,3-Oxidosqualene is an important intermediate in the biosynthesis of membrane sterols, being converted to lanosterol by 2,3-oxidosqualene cyclase.
Featured in Publications
1) Buurman, E. T., A. E. Blodgett, et al. (2004). “Pyridines and Pyrimidines Mediating Activity against an Efflux-Negative Strain of Candida albicans through Putative Inhibition of Lanosterol Demethylase.” Antimicrobial Agents and Chemotherapy 48(1): 313-318.
2) D. C. Lamb, C. J. Jackson, A. G. Warrilow, N. J. Manning, D. E. Kelly and S. L. Kelly. (2007) “Lanosterol biosynthesis in the prokaryote Methylococcus capsulatus: insight into the evolution of sterol biosynthesis” Mol Biol Evol 24(8), 1714-21