L-3223 (GWJ-23 or GWJ-A-23) is a potent inhibitor of the enzyme autotaxin (Ki = 18 nM). It is an analog of the known ATX inhibitor S32826 and has improved aqueous solubility compared with the parent compound. GWJ-A-23 has been shown to reduce lung collagen, bronchoalveolar lavage cell counts, total protein, LPA, and TGF-β levels in an idiopathic pulmonary fibrosis mouse model (Ref. 2).
![[4-(Decanoylamino)benzyl]phosphonic acid (GWJ-23, GWJ-A-23) - Echelon Biosciences](https://www.echelon-inc.com/wp-content/uploads/2019/07/1342.gif "1342.gif")
Product Number: L-3223
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L-3223
[4-(Decanoylamino)benzyl] phosphonic acid (GWJ-23, GWJ-A-23)
L-3223 (GWJ-23 or GWJ-A-23) is a potent inhibitor of the enzyme autotaxin (Ki = 18 nM). [Read More...]
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