10 ug (Z-RV14)

Vac14, also known as ArPIKfyve, is a scaffold protein that functions in a complex with PIKfyve and Sac3 (FIG4). This complex regulates the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2) on endosomal membranes. Vac14 forms a pentamer at the membrane to facilitate assembly of the complex and binds a single copy each of PIKFYVE and Sac3. The coordinated lipid kinase and phosphatase activity within the complex maintains homeostasis of PI(3)P and PI(5)P and plays a role in the fusion and transport of endosomes.

Z-RV14 Vac14 antibody has been validated for WB, IP, and ICC and has been shown to recognize human and mouse/rat isoforms. The antibody was generated from a fusion protein with amino acids 523 to 782 of human Vac14.

We are in the process of migrating our technical data sheets (TDS) to this space. They can currently be found in the description section of the product pages. Thank you for your patience. For any technical questions, please contact us at echelon@echelon-inc.com

 

Storage

-80 °C or below

Shipping Temp

Dry Ice

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