Z-Phe-Arg-AMC (Kallikrein substrate)

Product Number: 871-75


SKU: 871-75 Category: Tag:

CAS Number: 65147-22-0
Molecular Weight: 612.27
Salt Form: TFA
Purity: >96%
Sequence (3-letter): Z-Phe-Arg-AMC
Sequence (1-letter): Z-FR-AMC
Storage: -20 °C or below

Z-Phe-Arg-AMC is a fluorogenic substrate for the serine protease plasma kallikrein. Kallikrein is responsible for the regulation of blood pressure and activation of inflammation by releasing kinins (bradykinin and kallidin) from kinogens. Z-FR-AMC will also act as a substrate for papain, trypsin, and cathepsins B, K, L, & S.

Activity is quantified by release of free fluorescent 7-amino-4-methylcoumarin (AMC) which excites at 360-380 nm and emits at 440-460 nm.

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Enzyme Substrates

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