Z-Ile-Glu-Thr-Asp-AFC (Granzyme B Substrate)

Product Number: 863-56

$150.00$573.00

$150.00
$573.00
SKU: 863-56 Category: Tags: ,

CAS Number: 219138-02-0
Molecular Weight: 821.76
Salt Form: N/A
Purity: >96%
Sequence (3-letter): Z-Ile-Glu-Thr-Asp-AFC
Sequence (1-letter): Z-IETD-AFC
Storage: -20 °C or below

Z-IETD-AFC is a fluorogenic substrate for Granzyme B. Granzyme B is a serine protease found in cytotoxic T-cells and NK cells. It cleaves and activates several caspases involved in apoptosis.

Activity is quantified by release of free fluorescent 7-amino-4-trifluoromethylcoumarin (AFC) which excites at 395-400 nm and emits at 495-505 nm.

We are in the process of migrating our technical data sheets (TDS) to this space. They can currently be found in the description section of the product pages. Thank you for your patience. For any technical questions, please contact us at echelon@echelon-inc.com

 

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Caspase, Enzyme Substrates

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