XY-4 (PPARγ agonist)

Product Number: L-1160

$161.70

$161.70
SKU: L-1160 Category: Tags: ,

(2R)-1,1-difluoro-2-palmitoyloxy-3-phosphopropane (XY-4) is an analog of 2-palmitoyl lysophosphatidic acid (LPA) in which the sn-1 hydroxyl has been replaced by two fluorines. It acts as a selective agonist of peroxisome proliferator-activated receptor γ (PPARγ) but does not stimulate LPA1, LPA2, or LPA3 receptors. PPARγ is a transcription factor of the nuclear receptor superfamily and has been implicated in atherogenesis.

Categories

Lipids

Filter

Lysophospholipid

CAS Number

474329-47-0

Molecular Formula

C19H37F2O6P

Molecular Weight (g/mol)

430.46

Purity

95%

Storage

-20 °C or below

Technical Data Sheet

1) Zhang, C., D. L. Baker, et al. (2004). “Lysophosphatidic Acid Induces Neointima Formation Through PPARgamma Activation.” The Journal of Experimental Medicine 199(6): 763-774.
2) McIntyre, T. M., A. V. Pontsler, et al. (2003). “Identification of an intracellular receptor for lysophosphatidic acid (LPA): LPA is a transcellular PPARgamma agonist.” Proceedings of the National Academy of Sciences 100(1): 131-136.

You may also like…

  • Oleoyl LPA, 18:1 LPA - Echelon Biosciences
    Lipids

    Oleoyl LPA, 18:1 LPA

    Product Number: L-0181

    $19.95$159.60 View products
Shopping Cart
Scroll to Top