Lyosphosphatidic Acid (LPA) Beads

Product Number: L-6101


Lipid coated beads are designed for use in protein pull-down experiments. Use to test for lipid binding of purified protein, proteins in cell lysate, or binding of radiolabeled <em>in vitro</em> translation products.

LPA beads are composed of agarose with 10 nanomoles of bound Lyosphosphatidic Acid (LPA) per mL of beads, enough for several protein binding experiments. Each 1 mL order of LPA Beads includes a small amount of control beads. Larger quantities of Control Beads are also available for purchase.


Biochemical Reagents


Beads, Lysophosphatidic Acid

Shipping Temp

Gel Ice


4-8 °C

Technical Data Sheet

Blog: Lipid-Ligand interaction tools: lipids are not scary intermediates anymore”

Blog: Identifying lipid-protein interactions with Lipid Beads and LC/MS

1) 1. A. S. Nieto-Posadas, G. Picazo-Juárez, et al. (2012) “Lysophosphatidic acid directly activates TRPV1 through a C-terminal binding site” Nat Chem Biol 8(1), 78-85 doi:10.1038/nchembio.712
2) R. Tsukahara, H. Haniu, et al. (2014) “Heart-type fatty-acid-binding protein (FABP3) is a lysophosphatidic acid-binding protein in human coronary artery endothelial cells” FEBS Open Bio 4(1), 947-951 DOI: 10.1016/j.fob.2014.10.014
3) S. L. Morales-Lazaro, B. Serrano-Flores, et al. (2014) “Structural Determinants of the Transient Receptor Potential 1 (TRPV1) Channel Activation by Phospholipid Analogs” J. Biol. Chem. 289(35), 24079-24090 10.1074/jbc.M114.572503

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