CAS Number: 128802-78-8
Molecular Weight: 665.29
Salt Form: N/A
Sequence (3-letter): Suc-Ala-Leu-Pro-Phe-pNA
Sequence (1-letter): Suc-ALPF-pNA
Storage: -20 °C or below
Suc-ALPF-pNA is a colorimetric substrate for peptidyl prolyl cis-trans isomerases (PPIases) including FK-506 binding proteins (FKBPs, also called macrophilins) and cyclophilins. PPIases, or rotamases, catalyze the cis-trans isomerisation of proline imidic peptide bonds to accelerate protein folding.
Activity is quantified by the release of p-nitroaniline which is measured by absorbance at 405 nm.