1-Palmitoyl-2-linoleoyl-sn-glycero-3-phosphoethanol (PLPEth) is a form of phosphatidylethanol (PEth), which is formed primarily by transphosphatidylation of phosphatidylcholine (PC) by phospholipase D. Most PEth (about 75%) is incorporated into erythrocyte membranes, and is one of the longest-lived circulating EtOH metabolite yet identified. PLPEth is a one of five most abundant naturally occurring PEth species.
PLPEth (16:0/18:2 PEth)
|Molecular Weight (g/mol)||
-20 °C or below
1) van der Nagel, B. C. H., et al. (2018). “Quantification of phosphatidylethanols in whole blood as a proxy for chronic alcohol consumption, using ultra performance convergence chromatography tandem mass spectrometry.” Ther Drug Monit 40(2): 268-275.
2) DiBattista, A., et al. (2022) “Quantitation of phosphatidylethanols in dried blood spots to determine rates of prenatal alcohol exposure in Ontario.” Alcoholism: Clinical and Experimental Research 46(2): 243-251.
3) Aboutara, N., et al. (2021). “Analysis of six different homologues of phosphatidylethanol from dried blood spots using liquid chromatography-tandem mass spectrometry.” Drug Test Anal 13(1): 140-147.