1-Palmitoyl-2-linoleoyl-sn-glycero-3-phosphoethanol (PLPEth) is a form of phosphatidylethanol (PEth), which is formed primarily by transphosphatidylation of phosphatidylcholine (PC) by phospholipase D. Most PEth (about 75%) is incorporated into erythrocyte membranes, and is one of the longest-lived circulating EtOH metabolite yet identified. PLPEth is a one of five most abundant naturally occurring PEth species.
Featured in Publications
1) van der Nagel, B. C. H., et al. (2018). “Quantification of phosphatidylethanols in whole blood as a proxy for chronic alcohol consumption, using ultra performance convergence chromatography tandem mass spectrometry.” Ther Drug Monit 40(2): 268-275.