PI(5)P diC8 (ammonium salt)

Product Number: P-5008A

$50.00$408.00

$50.00
$220.00
$408.00

Phosphatidylinositol 5-phosphate diC8 (ammonium salt) is a synthetic, purified dioctanoyl PI(5)P.

Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 5-phosphate (PI(5)P) is a rare lipid found in the nucleus that can bind the PHD finger of the nuclear adapter protein ING2. PI(5)P is phosphorylated to PI(4,5)P2 by Type II PIP kinases.

Featured in Publications:

1) Ikonomov, O. C., D. Sbrissa, et al. (2002). “Functional dissection of lipid and protein kinase signals of PIKfyve reveals the role of PtdIns 3,5-P2 production for endomembrane integrity.” J Biol Chem 277(11): 9206-11.
2) Hinchliffe, K. A., M. L. Giudici, et al. (2002). “Type IIalpha phosphatidylinositol phosphate kinase associates with the plasma membrane via interaction with type I isoforms.” Biochem J 363(Pt 3): 563-70.
3) Sbrissa, D., O. C. Ikonomov, et al. (2002). “Phosphatidylinositol 5-phosphate biosynthesis is linked to PIKfyve and is involved in osmotic response pathway in mammalian cells.” J Biol Chem 277(49): 47276-84.

Alternate Names: Dipalmitoyl Phosphatidylinositol 5-phosphate, PtdIns(5)P C8, PI(5)P C8, or PI5P

Bulk discounts available, please email echelon@echelon-inc.com for information.

Categories

Lipids

Filter

diC8, Phosphoinositides, PI(5)P

CAS Number

291527-92-9

Molecular Formula

C25H54N2O16P2

Molecular Weight (g/mol)

700.65

Purity

>95%

Storage

-20 °C or below


Technical Data Sheet

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