N-Stearoyl Ceramide 1-phosphate

Product Number: S-5018

$101
$384
$626

Ceramide 1-phosphate (C1P) is biosynthesized from ceramide by the intracellular enzyme Ceramide kinase. C1P inhibits cell apoptosis via inhibition of acid sphingomyelinase activity in contrast to ceramide which promotes apoptosis. C1P is important in inflammation, activating cytosolic phospholipase A2 alpha and releasing downstream inflammatory mediators. In addition, C1P is involved in DNA synthesis, mast cell degranulation and neutrophil phagocytosis.

Categories

Lipids

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Ceramide, Sphingolipid

CAS Number

202063-34-1 (free acid), 384835-48-7 (ammonium salt)

Molecular Formula

C36H75N2O6P

Molecular Weight (g/mol)

662.96

Purity

0.95

Storage

-20 °C or below

Shipping Temp

Gel Ice

Technical Data Sheet

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