mPEG-DSPE, 2000 is a derivative of phosphatidylethanolamine and is used to increase the circulation time of liposomes and lipid nanoparticles (LNPs) in vivo. The hydrophilic PEG chains decrease interactions with the reticular-endothelial system and increases the size of the particles both of which result in lowered clearance rate from the body.
| Categories | Lipids |
|---|---|
| Filter | Phosphatidylethanolamine |
| CAS Number | 474922-77-5 |
| Molecular Formula | (C2H4O)x-C43H83NO10PNa |
| Molecular Weight (g/mol) | ~2820 (mPEG MW = 2000 Da) |
| Purity | >95% |
| Storage | -20 °C or below |
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