MCA-Pro-Leu-Ala-Cys(p-MeOBz)-Trp-Ala-Arg-Dap(DNP)-NH2 (MMP-11, MMP-14 substrate)

Product Number: 868-42

$158$602

$158
$602
SKU: 868-42 Category: Tag:

CAS Number: 1926163-82-7
Molecular Weight: 1402.58
Salt Form: TFA
Purity: >96%
Sequence (3-letter): MCA-Pro-Leu-Ala-Cys(p-MeOBz)-Trp-Ala-Arg-Dap(DNP)-NH2
Sequence (1-letter): MCA-PLAC(p-MeOBz)WAR(Dap(DNP))-NH2
Storage: -20 °C or below

MCA-Pro-Leu-Ala-Cys(p-MeOBz)-Trp-Ala-Arg-Dap(DNP)-NH2 is a FRET substrate for MMP-11 (Stromelysin-3) and MMP-14 (MT1-MMP). It has kcat/Km values of 3.6 · 10⁴ M⁻¹s⁻¹ and 7.3 · 10⁵ M⁻¹s⁻¹, when assayed with MMP-11 and MMP-14, respectively.

Activity is quantified by fluorescence (Ex 325 nm, Em at 393 nm).

 

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