Lipid OA2

Product No: N-1002

$104
$205
$656

Lipid OA2 is an ionizable lipid which can form single component lipid nanoparticles (LNPs) for delivery of RNA. Similar to lipid-based transfection reagents like LipofectamineTM, pre-formed OA2 vesicles are incubated with RNA then the mixture is directly added cells. OA2 LNPs delivered siRNA to downregulate cytokine signaling 1 (SOCS1) in mouse bone marrow dentritic cells. These SOCS downregulated DCs were used as a vaccine which reduced tumor size in a B16-OVA mouse model.

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Lipids

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Ionizable/Cationic Lipids

Molecular Formula

C47H91Cl2N3O5

Molecular Weight (g/mol)

849.16

Purity

>90%

Storage

-20 °C or below

Shipping Temp

Ambient Temperature

Technical Data Sheet

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