Lipid A6 is an ionizable and biodegradable lipid. Lipid A6 has similar structure as Dlin-MC3-DMA but with ester and alkyne bonds to improve its biodegradability and cell membrane fusion ability. Lipid A6 forms lipid-like nanoparticles together with cKK-E12 synergistically to facilitate robust mRNA delivery with improved tolerability. MC3 is the key delivery nanoparticle component of the first siRNA drug Onpattro.
| Categories | Lipids |
|---|---|
| Filter | Ionizable/Cationic Lipids |
| Molecular Formula | C43H75NO6 |
| Molecular Weight (g/mol) | 702.07 |
| Purity | >95% |
| Storage | -20 °C or below |
