Inositol phosphates are important signaling molecules involved in numerous cellular functions. Inositol 1,4-bisphosphate (Ins(1,4)P2) is an intermediate in the inositol phosphate pathway. It is produced by dephosphorylation of Ins(1,4,5)P3 by a 5-phosphatase thus terminating IP3 signaling. Ins(1,4)P2 is also a substrate for inositol 1-phosphatase.
“Phosphatidylinositol and inositol phosphate metabolism.” J. Cell Sci. 2001, 114, 2207-8.
Keywords: D-myo-Inositol 1,4-bisphosphate, Ins(1,4)P2, or I(1,4)P2
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