Acetyl Hirudin (54-65), Sulfated

Product Number: 873-15


CAS Number: 125441-00-1
Molecular Weight: 1589.61
Salt Form: NH4+
Purity: >96%
Sequence (3-letter): Ac-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr(SO3H)-Leu-Gln-OH
Sequence (1-letter): Ac-GDFEEIPEE(Tyr(SO3H))LQ-OH
Storage: -20 °C or below

Hirudin is a naturally occurring 65-amino acid peptide in the saliva of blood-sucking leeches and has anti-coagulating properties. This sulfated fragment binds to the regulatory exosite of thrombin 1 and prevents the activation of clotting factor V.

Reference: Van Deerlin, V. et al. J. Biol. Chem .(1997) 266, 20223.





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