GroPI

Product Number: P-0000

$133.00$695.00

$133.00
$402.00
$695.00
SKU: P-0000- Category: Tags: , ,

Glycerophosphoinositol (GroPI) is the building block for phosphoinositide polyphosphates and is a substrate for PI-PLC.

Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol (PI or PtdIns) is biosynthesized from CDP-diacylglycerol and inositol by phosphatidylinositol synthase. PI is the building block for phosphoinositide polyphosphates through phosphorylation by PI-kinases and is a substrate for PI-PLC yielding diacylgelycerol.

Bulk discounts available, please email echelon@echelon-inc.com for information.

Categories

Lipids

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Glycerolphosphoinositide, Phosphoinositides

CAS Number

129830-95-1

Molecular Formula

C9H18NaO11P

Molecular Weight (g/mol)

356.20

Purity

>95%

Storage

-20 °C or below

Technical Data Sheet

1) Zizza, P., C. Iurisci, et al. (2012). “Phospholipase A2 IValpha regulates phagocytosis independent of its enzymatic activity.” J Biol Chem 287(20): 16849-16859.
2) Vessichelli, M., et al. (2017). “The natural phosphoinositide derivative glycerophosphoinositol inhibits the lipopolysaccharide-induced inflammatory and thrombotic responses.” Journal of Biological Chemistry 292(31): 12828-12841.

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