GroPI

Product Number: P-0000

$154
$465
$805

Glycerophosphoinositol (GroPI) is the building block for phosphoinositide polyphosphates and is a substrate for PI-PLC.

Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol (PI or PtdIns) is biosynthesized from CDP-diacylglycerol and inositol by phosphatidylinositol synthase. PI is the building block for phosphoinositide polyphosphates through phosphorylation by PI-kinases and is a substrate for PI-PLC yielding diacylgelycerol.

Bulk discounts available, please email echelon@echelon-inc.com for information.

Categories

Lipids

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Glycerolphosphoinositide, Phosphoinositides

CAS Number

129830-95-1

Molecular Formula

C9H18NaO11P

Molecular Weight (g/mol)

356.2

Purity

>95%

Storage

-20 °C or below

Shipping Temp

Dry ice or gel ice depending on destination

Technical Data Sheet

1) Zizza, P., C. Iurisci, et al. (2012). “Phospholipase A2 IValpha regulates phagocytosis independent of its enzymatic activity.” J Biol Chem 287(20): 16849-16859.
2) Vessichelli, M., et al. (2017). “The natural phosphoinositide derivative glycerophosphoinositol inhibits the lipopolysaccharide-induced inflammatory and thrombotic responses.” Journal of Biological Chemistry 292(31): 12828-12841.

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