GloPIPs Biotin-PI(3,4)P2

Product Number: C-34B6A

$232.00$710.00

$232.00
$710.00
SKU: C-34B6A- Category: Tags: , , , ,

Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3,4-bisphosphate (PI(3,4)P2) is produced in stimulated cells by the action of phosphatidylinositol 3-kinases (PI3Ks) and/or lipid phosphatases (SHIP, TPTE, etc.). PI(3,4)P2 binds the pleckstrin homology (PH)-domain of AKT/PKB leading to cell survival and it also has an important role in podosome formation near focal adhesions.


GloPIPs are labeled at the sn-1 position with BODIPY®-FL (505/513), BODIPY®-TMR (544/574), or biotin. The sn-1 linkage in these labeled PIPs has been changed to a more stable amide from an ester. Results from experiments conducted at Echelon indicated that this minor chemical change did not have a significant effect in any of the applications tested.

Bulk discounts available, please email echelon@echelon-inc.com for information.


Categories

Lipids

Filter

Biotinylated, Phosphoinositides, PI(3,4)P2

Molecular Formula

C31H52N4Na5O20P3S

Molecular Weight (g/mol)

1,040.7

Purity

>95%

Storage

-20 °C or below

Technical Data Sheet

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