Ac-Thr-Gln-Thr-Glu-AFC (DRONC Substrate I)

Molecular Weight: 730.24
Salt Form: N/A
Purity: >96%
Sequence (3-letter): Ac-Thr-Gln-Thr-Glu-AFC
Sequence (1-letter): Ac-TQTE-AFC
Storage: -20 °C or below

DRONC is a caspase found in Drosophila which is likely to be involved in programmed cell death during insect metamorphosis.  The substrate specificity of DRONC is similar to mammalian caspase-2.

Activity is quantified by release of free fluorescent 7-amino-4-trifluoromethylcoumarin (AFC) which excites at 395-400 nm and emits at 495-505 nm.