d5-D-myo-Phosphatidylinositol 3,4,5-trisphosphate DiC16

P-3916d

$61.00$481.00

$61.00
$271.00
$481.00
SKU: P-3916d Category: Tags: , ,

Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3,4,5-trisphosphate (PIP3), formed from PI(4,5)P2 though phosphorylation by PI 3-kinase, activates numerous signaling pathways resulting in cell proliferation, growth, survival, glucose transport and protein synthesis. High PIP3 levels from dysregulation of PI3-K have been demonstrated in cancer and inflammatory diseases. PIP3 is hydrolyzed by the phosphatases PTEN to PI(4,5)P2 and SHIP to PI(3,4)P2. This analog is deuterated at the glycerol.

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Deuterated Lipids, Phosphoinositides, PI(3,4,5)P3

Categories

Lipids

Molecular Formula

C41H73D5Na4O22P4

Molecular Weight (g/mol)

1143.94

Purity

95%

Storage

-20 °C or below

Technical Data Sheet

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