Cathepsin S Substrate, fluorogenic

Product Number: 866-80

$190.00

$190.00
SKU: 866-80 Category: Tag:

CAS Number: 1135686-31-5
Molecular Weight: 870.51
Salt Form: TFA
Purity: >95%
Sequence (3-letter): Ac-Lys-Gln-Lys-Leu-Arg-AMC
Sequence (1-letter): Ac-KQKLR-AMC
Storage: -20 °C or below

Ac-KQKLR-AMC is a fluorogenic substrate for Cathepsin S. Cathepsin S is a lysosomal cysteine protease with important roles in MHC Class II antigen presentation and nociception. Cathepsin S also cleaves several extracellular matrix proteins (laminin, fibronectin elastin, osteocalcin) and glycosaminoglycans (heparin sulfate, chondroitin sulfate).

Activity is quantified by release of free fluorescent 7-amino-4-methylcoumarin (AMC) which excites at 360-380 nm and emits at 440-460 nm.

We are in the process of migrating our technical data sheets (TDS) to this space. They can currently be found in the description section of the product pages. Thank you for your patience. For any technical questions, please contact us at echelon@echelon-inc.com

 

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