Cathepsin L Inhibitor (RKLLW-NH2)

Product Number: 866-23

$91.00

$91.00
SKU: 866-23 Category: Tag:

CAS Number: 289480-71-3
Molecular Weight: 713.47
Salt Form: TFA
Purity: >96%
Sequence (3-letter): Arg-Lys-Leu-Leu-Trp-NH2
Sequence (1-letter): RKLLW-NH2
Storage: -20 °C or below

Cathepsin L is a lysosomal cysteine protease with an important role in initiating protein degradation. Cathepsin L is also upregulated in several cancers and has been suggested as a drug target. In addition, extracellular secretion of Cathepsin L by tumors implicates it as a potential serum biomarker for  cancer progression. The inhibitor has a low micromolar IC50.

References:
1) A. Brinker, et al. (2000) “Highly potent inhibitors of human cathepsin L identified by screening combinatorial pentapeptide amide collections” Eur. J. Biochem. 267, 5085-5092.

We are in the process of migrating our technical data sheets (TDS) to this space. They can currently be found in the description section of the product pages. Thank you for your patience. For any technical questions, please contact us at echelon@echelon-inc.com

 

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