Calcitonin, salmon [Des-Tyr22]

Molecular Weight: 3268.68
Salt Form: TFA
Purity: >95%
Sequence (3-letter): Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2
Sequence (1-letter): CSNLSTCVLGKLSQELHKLQTPRTNTGSGTP-NH2
Storage: -20 °C or below

Calcitonin is cyclic peptide hormone that stimulates bone formation by osteoblasts and inhibits bone resorption. Calcitonin is a hypocalcemic hormone produced by the parafollicular C cells of the thyroid or by the ultimobranchial bodies of non-mammalian vertebrates. It decreases blood calcium and phosphate due to inhibition of resorption by osteoblasts and osteocytes. Calcitonin, salmon [Des-Tyr22] is an analogue of calcitonin with reduced adenylate cyclase activation activity (in vitro). In isolated rat pituitary cells, it exhibits lowered inhibitory activity for prolactin release.