Bz-Arg-Gly-Phe-Phe-Pro-4MbNA (Cathepsin D Substrate)

Product Number: 880-42

$99.00

$99.00
SKU: 880-42 Category: Tags: ,

Molecular Weight: 881.42
Salt Form: HCl
Purity: >96%
Sequence (3-letter): Bz-Arg-Gly-Phe-Phe-Pro-4MbNA
Sequence (1-letter): Bz-RGFFP-4MbNA
Storage: -20 °C or below

Bz-Arg-Gly-Phe-Phe-Pro-4MbNA is a fluorogenic substrate for Cathepsin D. Cathepsin D is a lysosomal aspartyl protease whose role is to degrade and activate intracellular proteins including hormones, enzyme precursors, and growth factors. Over expression in tumors stimulates metastasis and considered a marker of poor prognosis in breast cancer.

Activity is quantified by release of free fluorescent 4-Methoxy-β-naphthylamine (4MβNA) which excites at 335-350 nm and emits at 410-440 nm.

We are in the process of migrating our technical data sheets (TDS) to this space. They can currently be found in the description section of the product pages. Thank you for your patience. For any technical questions, please contact us at echelon@echelon-inc.com

 

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Caspase, Enzyme Substrates

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