BODIPY FL Phosphatidylinositol 4,5-bisphosphate

Product Number: C-45F6


BODIPY FL Phosphatidylinositol 4,5-bisphosphate is a water soluble analog of PI(4,5)P2 (PIP2) labeled with the green fluorophore, Bodipy®-FL, at the sn-1 position.

Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 4,5-bisphosphate (PIP2) has been shown to play a central role in a variety of cellular functions. Amongst its many functions, PIP2 is a substrate for Phospholipase C-coupled G-protein pathways involved in intracellular calcium release in a number of tissues. It is also a substrate for class I phosphoinositide 3-kinase (PI3-K) forming PI(3,4,5)P3.


503/513 nm


-20 °C, protect from light


1) Caromile, L. A., A. Oganesian, et al. (2010). “The neurosecretory vesicle protein phogrin functions as a phosphatidylinositol phosphatase to regulate insulin secretion.” J Biol Chem 285(14): 10487-96.
2)Rudge, S. A., D. M. Anderson, et al. (2004). “Vacuole size control: regulation of PtdIns(3,5)P2 levels by the vacuole-associated Vac14-Fig4 complex, a PtdIns(3,5)P2-specific phosphatase.” Mol Biol Cell 15(1): 24-36.
3) Oganesian, A., M. Poot, et al. (2003). “Protein tyrosine phosphatase RQ is a phosphatidylinositol phosphatase that can regulate cell survival and proliferation.” Proc Natl Acad Sci U S A 100(13): 7563-8.
4) Omar-Hmeadi, M, Gandasi, N, Barg, S (2018). “PtdIns(4,5)P2 is not required for secretory granule docking” Traffic, DOI:10.1111/tra.12562

Bulk discounts available, please email for information.




Fluorescent, Phosphoinositides, PI(4,5)P2


503/513 nm

Molecular Formula


Molecular Weight (g/mol)





-20 °C or below, protect from light

Technical Data Sheet

You may also like…

  • Phosphatidylinositol 4,5-bisphosphate diC8 (PI(4,5)P2 diC8) - Echelon Biosciences

    PI(4,5)P2 diC8

    Product Number: P-4508

    $46$376 View products
  • Phosphatidylinositol 4,5-bisphosphate diC4 (PI(4,5)P2 diC4) - Echelon Biosciences

    PI(4,5)P2 diC4

    Product Number: P-4504

    $134$710 View products
  • Phosphatidylinositol 4,5-bisphosphate diC16 (PI(4,5)P2 diC16) - Echelon Biosciences

    PI(4,5)P2 diC16

    Product Number: P-4516

    $61$504 View products
  • BODIPY TMR PI(4,5)P2 - Echelon Biosciences

    BODIPY TMR PI(4,5)P2

    Product Number: C-45M6

    $456$783 View products
Shopping Cart
Scroll to Top

Technical Support

Bulk & Custom Orders