AS1938909 (SHIP2 Inhibitor)

Product Number: B-0343

$92.00$379.00

$92.00
$169.00
$379.00
SKU: B-0343- Category: Tags: , , , ,

AS1938909 is a potent SHIP2 inhibitor (Ki = 0.44uM). This compound shows signficant selectivity over some related phosphatases (IC50 = 0.18uM, 21uM, >50uM for mSHIP2, hSHIP2, hPTEN respectively). It also enhances Akt phosphorylation and increases glucose consumption and uptake in L6 myotubes.

References

A Suwa, T Yamanoto et al. “Glucose metabolism activation by SHIP2 inhibitors via up-regulation of GLUT1 gene in L6 myotubes” Eur J Pharmaco, 2010, 642, 177


Categories

Biochemical Reagents

Filter

Inhibitor, SHIP

CAS Number

1243155-40-9

Molecular Formula

C19H13Cl2F2NO2S

Molecular Weight (g/mol)

428.28

Purity

>95%

Storage

4 °C or below

Technical Data Sheet

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