AS1938909 is a potent SHIP2 inhibitor (Ki = 0.44uM). This compound shows signficant selectivity over some related phosphatases (IC50 = 0.18uM, 21uM, >50uM for mSHIP2, hSHIP2, hPTEN respectively). It also enhances Akt phosphorylation and increases glucose consumption and uptake in L6 myotubes.
| Categories | Biochemical Reagents |
|---|---|
| Filter | Inhibitor, SHIP |
| CAS Number | 1243155-40-9 |
| Molecular Formula | C19H13Cl2F2NO2S |
| Molecular Weight (g/mol) | 428.28 |
| Purity | >95% |
| Storage | 4 °C or below |
You may also like…
-
-
Biochemical Reagents3-a-Aminocholestane (3AC, SHIP1 Inhibitor)
$85 – $347 View productsProduct Number: B-0341
-
-
Kits & Assays5′ PtdIns(3,4,5)P3 Phosphatase Activity Fluorescence Polarization Assay
$632 View productsProduct Number: K-1400
Related products
-
-
Biochemical ReagentsNVP-231 (Ceramide Kinase Inhibitor)
$25 – $80 View productsProduct Number: B-0040
-
-
Biochemical ReagentsFS-3 (LysoPLD / Autotaxin substrate)
$345 – $2,788 View productsProduct Number: L-2000