AS1938909 is a potent SHIP2 inhibitor (Ki = 0.44uM). This compound shows signficant selectivity over some related phosphatases (IC50 = 0.18uM, 21uM, >50uM for mSHIP2, hSHIP2, hPTEN respectively). It also enhances Akt phosphorylation and increases glucose consumption and uptake in L6 myotubes.
| Categories | Biochemical Reagents |
|---|---|
| Filter | Inhibitor, SHIP |
| CAS Number | 1243155-40-9 |
| Molecular Formula | C19H13Cl2F2NO2S |
| Molecular Weight (g/mol) | 428.28 |
| Purity | >95% |
| Storage | 4 °C or below |
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