Allatostatin B2, cockroach

CAS Number: 134760-78-4
Molecular Weight: 2167.11
Salt Form: TFA
Purity: >96%
Sequence (3-letter): Ala-Tyr-Ser-Tyr-Val-Ser-Glu-Tyr-Lys-Arg-Leu-Pro-Val-Tyr-Asn-Phe-Gly-Leu-NH2
Sequence (1-letter): AYSYVSEYKRLPVYNFGL-NH2
Storage: -20 °C or below

Allostatin B2 (ASB2) is a myoinhibitory peptide (MIP) used to study juvenile hormone production.  Allatostatins are neuropeptides found in insects and crustaceans and Allatostatin B2 inhibits juvenile hormone biosynthesis in insects. As a result, Allatostatin B2 is a potential target for insecticide development.

References

Williamson M, Lenz C, Winther AM, Nässel DR, Grimmelikhuijzen CJ (2001) “Molecular cloning, genomic organization, and expression of a B-type (cricket-type) allatostatin preprohormone from Drosophila melanogaster”. Biochem Biophys Res Commun. 281(2):544-50.