Ac-Orn-Phe-Arg-AMC (Tryptase Substrate, fluorogenic)

Molecular Weight: 634.32
Salt Form: TFA
Purity: >96%
Sequence (3-letter): Ac-Orn-Phe-Arg-AMC
Sequence (1-letter): Ac-(Orn)FR-AMC
Storage: -20 °C or below

Ac-Orn-Phe-Arg-AMC is a fluorogenic substrate for tryptase. Tryptase is a serine protease from mast cells and is iused as a marker for mast cell activation.

Activity is quantified by release of free fluorescent 7-amino-4-methylcoumarin (AMC) which excites at 360-380 nm and emits at 440-460 nm.