Ac-Leu-Glu-His-Asp-AFC (Caspase 9 Substrate)

Product Number: 863-40


SKU: 863-40 Category: Tags: ,

CAS Number: 210345-03-2
Molecular Weight: 765.27
Salt Form: TFA
Purity: >96%
Sequence (3-letter): Ac-Leu-Glu-His-Asp-AFC
Sequence (1-letter): Ac-LEHD-AFC
Storage: -20 °C or below

Ac-Leu-Glu-His-Asp-AFC is a fluorogenic substrate for caspase 9. Caspase 9 is a cysteine protease which acts as an initiating enzyme in apoptosis pathways. It activates Caspases 3, 6, & 7.

Activity is quantified by release of free fluorescent 7-amino-4-trifluoromethylcoumarin (AFC) which excites at 395-400 nm and emits at 495-505 nm.

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Caspase, Enzyme Substrates

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