9(10)-Nitrooleic Acid

Product Number: L-0112

$111
$210

Nitrooleic acid (OA-NO2) is formed by nitration of oleic acid from excessive nitric oxide during inflammation (nitrative stress). OA-NO2 is a potent signaling molecule which can activate numerous receptors including TRPA1 cation channels and PPARγ. 9(10)-Nitrooleic acid is a mixture of the 9-nitro and 10-nitro isomers which are formed in equal amounts in vivo.

References

1. P.S. Baker et al “Fatty Acid Transduction of Nitric Oxide signaling” Journal of Biological Chemistry, 2005, 280, 42464-42475;
2. F.J. Schopfer et al “Covalent Peroxisome Proliferator-Activated Receptor Adduction By Nitro-Fatty Acid” Journal of Biological Chemistry, 2010, 285, 12321-12333.

Categories

Lipids

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Fatty Acid

CAS Number

875685-44-4 (875685-46-4)

Molecular Formula

C18H33NO4

Molecular Weight (g/mol)

327.24

Storage

-20 °C or below

Technical Data Sheet

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