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Genetic therapies have now been pursued for several decades and close to a dozen DNA-based gene therapies have gained regulatory …

Lipid Nanoparticles for RNA Delivery Read More »

Coauthored with Jeff Johnson and Melissa Burback According to a May 2022 report from the World Health Organization (WHO), 3 …

Semi-quantitative PEth ELISA holds promise for simplifying clinical analysis of alcohol consumption Read More »

Coauthored with Patrick McDaniel from HTL From dermal fillers to eye drops and from drug delivery to tissue engineering, hyaluronic …

Methacrylated Hyaluronic Acid: Benefits and Applications Read More »

PIKfyve, also known as PIP5K3, is a lipid kinase that synthesizes two rare phosphoinositides, PI(5)P and PI(3,5)P2 (Figure 1). The …

PIKfyve: function and inhibition as therapeutic opportunities Read More »

Lipid Coated Beads are lipid-protein interaction tools originally conceived around eight phosphatidylinositol phosphate coatings that have since expanded to 26 …

Identifying lipid-protein interactions with Lipid Beads and LC/MS Read More »

Since the discovery of hyaluronic acid (HA) in the 1930s, new functional roles of this special polymer continue to be …

Tools For Hyaluronic Acid Research Read More »

In late 2021 an elegant study was published that identified the molecular basis for protection of a rare coding variant …

Intracellular Delivery of Phosphoinositides Read More »

Most molecular and cell biologists have an array of techniques in their toolkit that make use of conventional IgG or …

Nanobodies: production, applications, and more Read More »

Echelon’s ELISAs are centered around biologically interesting lipids and extracellular matrix molecules such as Hyaluronic acid. Lipids are known to …

What is a Competitive ELISA? Read More »

Isoprenoids are an amazingly diverse and biologically important class of molecules. They are some of the oldest known biomolecules, with …

Isoprenoids: Biology and Potential Uses Read More »