Autotaxin (ATX) Activity Assay Service

The Autotaxin (ATX) Activity Assay Service uses the Autotaxin Activity Assay Kit (cat # K-4100) to quantify ATX activity in biological samples. ATX is an extracellular enzyme that cleaves lysophosphatidylcholine (LPC) to generate the phospholipid growth factor lysophophatidic acid (LPA). LPA is involved in a variety of biological functions, such as angiogenesis, wound healing, vascular and nervous system development, reproduction, pain transmission, immunological competence and the regulation of blood pressure. Altered LPA biology is associated with a number of diseases. Likewise, autotaxin has been implicated in a number of disorders, including a variety of cancers, obesity, arthritis, multiple sclerosis, Alzheimer’s disease and neuropathic pain.

  • Echelon has 25 years of assay development expertise and 15 years experience in the ATX field.
  • Your samples are cataloged and stored according to your requirements.
  • The Autotaxin Activity Assay Service will run each sample in duplicate.
  • Results are provided as an average of duplicate points in ATX units.
  • Usually results are provided 2 weeks from receipt of samples. We can accommodate tighter schedules if needed.

Contact us for a quote on your custom assay service.

Description

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Publications

Citations listed are from the Autotaxin Activity Assay (catalog number K-4100).

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