C14-306

C14-306 is an ionizable lipid used for formulating lipid nanoparticles (LNPs) for delivering RNA. [Read More...]

C14-306 is an ionizable lipid used for formulating lipid nanoparticles (LNPs) for delivering RNA. LNP formulations withC14-306 demonstrated enhanced delivery to the brain and neuronal transfection of Cre mRNA in a mouse model. C14-306 LNPs did not cause appreciable systemic inflammation or disrupt the blood brain barrier.