Z-Phe-Tyr-CHO (Cathepsin L Inhibitor)

Product Number: 866-28


SKU: 866-28 Category: Tag:

CAS Number: 167498-29-5
Molecular Weight: 446.18
Salt Form: N/A
Purity: >95%
Sequence (3-letter): Z-Phe-Tyr-CHO
Sequence (1-letter): Z-FY-CHO
Storage: -20 °C or below

Z-Phe-Tyr-CHO is a reversible peptidyl aldehyde inhibitor of Cathepsin L (IC50=0.85 nM).  It is selective vs cathepsin B and calpain II (IC50s=85.1 and 184 nM respectively). Cathepsin L is a lysosomal cysteine protease with an important role in initiating protein degradation. Cathepsin L is also upregulated in several cancers and has been suggested as a drug target. In addition, extracellular secretion of Cathepsin L by tumors implicates it as a potential serum biomarker for cancer progression.

We are in the process of migrating our technical data sheets (TDS) to this space. They can currently be found in the description section of the product pages. Thank you for your patience. For any technical questions, please contact us at echelon@echelon-inc.com






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