Molecular Weight: 730.28
Salt Form: N/A
Sequence (3-letter): Z-Ile-Glu-Thr-Asp-pNA
Sequence (1-letter): Z-IETD-pNA
Storage: -20 °C or below
Z-IETD-pNA is a colorimetric substrate for Granzyme B. Granzyme B is a serine protease found in cytotoxic T-cells and NK cells. It cleaves and activates several caspases involved in apoptosis.
Activity is quantified by the release of p-nitroaniline which is measured by absorbance at 405 nm.