Z-Ala-Lys-Arg-AMC

Molecular Weight: 664.77
Salt Form: TFA
Purity: >96%
Sequence (3-letter): Z-Ala-Lys-Arg-AMC
Sequence (1-letter): Z-AKR-AMC
Storage: -20 °C or below

Z-Ala-Lys-Arg-AMC is a fluorogenic substrate for IRCM-Serine Protease 1. Activity is quantified by release of free fluorescent 7-amino-4-methylcoumarin (AMC) which excites at 360-380 nm and emits at 440-460 nm.

Reference: J.A. Cromlish, et al. “A Novel Serine Protease (IRCM-Serine Protease 1) from Porcine Neurointermediate and Anterior Pituitary Lobes” (1986) J Biol. Chem. 261 (23), 10850-1085.