Z-Ala-Arg-Arg-MbNA (Cathepsin B Substrate II)

Product Number: 866-29


SKU: 866-29 Category: Tag:

Molecular Weight: 690.36
Salt Form: TFA
Purity: >96%
Sequence (3-letter): Z-Ala-Arg-Arg-4MbNA
Sequence (1-letter): Z-ARR-4MbNA
Storage: -20 °C or below

Z-Ala-Arg-Arg-4MbNA is a fluorogenic substrate for Cathepsin B. Cathepsin B is a lysosomal cysteine protease with a role in intracellular protein degradation. Cathepsin B crosses the blood-brain barrier and elevated levels are implicated in many neurological maladies including traumatic brain injury, epilepsy, and Alzheimer’s disease.

Activity is quantified by release of free fluorescent 4-Methoxy-β-naphthylamine (4MβNA) which excites at 335-350 nm and emits at 410-440 nm

We are in the process of migrating our technical data sheets (TDS) to this space. They can currently be found in the description section of the product pages. Thank you for your patience. For any technical questions, please contact us at echelon@echelon-inc.com





Enzyme Substrates

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