XY-17 (LPA3 Agonist)

Product Number: L-9118

$341.00

$341.00

XY-17 is a fluorinated phosphonate analog of lysophosphatidic acid (LPA). XY-17 is not hydrolyzed by lipid phosphate phosphatase (LPP) and acts as an agonist of the LPA3 receptor.


Storage

-20 °C

Alternate Name: (3S)-1-fluoro-3-hydroxy-4-butyl-1-phosphonate (FHBP)

Featured in Publications

1) Xu, Y., M. Tanaka, et al. (2004). “Alkyl lysophosphatidic acid and fluoromethylene phosphonate analogs as metabolically-stabilized agonists for LPA receptors.” Bioorg Med Chem Lett 14(21): 5323-8.
2) Zhao, Y., P. V. Usatyuk, et al. (2005). “Lipid phosphate phosphatase-1 regulates lysophosphatidic acid-induced calcium release, NF-kappaB activation and interleukin-8 secretion in human bronchial epithelial cells.” Biochem. J. 385(2): 493-502.
3) Prestwich, G., Y. Xu, et al. (2005). “New metabolically stabilized analogues of lysophosphatidic acid: agonists, antagonists and enzyme inhibitors.” Biochem Soc Trans 33: 1357–1361.
4) W.N. Ayre, T. Scott, et al. (2016) “Fluorophosphonate-functionalised titanium via a pre-adsorbed alkane phosphonic acid: a novel dual action surface finish for bone regenerative applications.” J Mater Sci Mater Med. Feb;27(2):36. doi: 10.1007/s10856-015-5644-7


Documents

Technical Data Sheet

We are in the process of migrating our technical data sheets (TDS) to this space. They can currently be found in the description section of the product pages. Thank you for your patience. For any technical questions, please contact us at echelon@echelon-inc.com

 

Categories

Biochemical Reagents

Filter

Agonist, Lysophosphatidic Acid

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