XY-17 (LPA3 Agonist)

Product Number: L-9118



XY-17 is a fluorinated phosphonate analog of lysophosphatidic acid (LPA). XY-17 is not hydrolyzed by lipid phosphate phosphatase (LPP) and acts as an agonist of the LPA3 receptor.


-20 °C

Alternate Name: (3S)-1-fluoro-3-hydroxy-4-butyl-1-phosphonate (FHBP)

Featured in Publications

1) Xu, Y., M. Tanaka, et al. (2004). “Alkyl lysophosphatidic acid and fluoromethylene phosphonate analogs as metabolically-stabilized agonists for LPA receptors.” Bioorg Med Chem Lett 14(21): 5323-8.
2) Zhao, Y., P. V. Usatyuk, et al. (2005). “Lipid phosphate phosphatase-1 regulates lysophosphatidic acid-induced calcium release, NF-kappaB activation and interleukin-8 secretion in human bronchial epithelial cells.” Biochem. J. 385(2): 493-502.
3) Prestwich, G., Y. Xu, et al. (2005). “New metabolically stabilized analogues of lysophosphatidic acid: agonists, antagonists and enzyme inhibitors.” Biochem Soc Trans 33: 1357–1361.
4) W.N. Ayre, T. Scott, et al. (2016) “Fluorophosphonate-functionalised titanium via a pre-adsorbed alkane phosphonic acid: a novel dual action surface finish for bone regenerative applications.” J Mater Sci Mater Med. Feb;27(2):36. doi: 10.1007/s10856-015-5644-7


Technical Data Sheet

We are in the process of migrating our technical data sheets (TDS) to this space. They can currently be found in the description section of the product pages. Thank you for your patience. For any technical questions, please contact us at echelon@echelon-inc.com



Biochemical Reagents


Agonist, Lysophosphatidic Acid

You may also like…

  • GRI977143 (LPA2 Agonist) - Echelon Biosciences
    Biochemical Reagents

    GRI977143 (LPA2 Agonist)

    Product Number: B-0070

    $186.00$710.00 View products
  • Ki16425 (LPA Receptor Antagonist)
    Biochemical Reagents

    Ki16425 (LPA Receptor Antagonist)

    Product Number: B-0730

    $54.00$418.00 View products
  • 2S-OMPT, LPA3 agonist - Echelon Biosciences
    Biochemical Reagents


    Product Number: L-9418

    $71.00$443.00 View products
  • BrP-LPA (LPA bromophosphonate) - Echelon Biosciences
    Biochemical Reagents


    Product Number: L-7416

    $138.00$621.00 View products
Shopping Cart
Scroll to Top