Substrate for Factor VIIa

Molecular Weight: 701.28
Salt Form: TFA
Purity: >96%
Sequence (3-letter): Methylsulfonyl-D-Cha-Abu-Arg-AFC
Sequence (1-letter): (Methylsulfonyl)(Cha)(Abu)R-AFC
Storage: -20 °C or below

Methylsulfonyl-D-Cha-Abu-Arg-AFC is a fluorogenic substrate for Factor VIIa, a serine protease in the coagulation cascade.

Activity is quantified by release of free fluorescent 7-amino-4-trifluoromethylcoumarin (AFC) which excites at 395-400 nm and emits at 495-505 nm.