S32826

Product Number: L-3282

$78
$193

S32826  [4-(Tetradecanoylamino) benzyl]phosphonic acid disodium salt] is a potent inhibitor of the enzyme autotaxin, with an IC50 in the nanomolar range. S32826 is suitable for in vitro studies using purified components or cultured cells. Due to its short circulation half-life, S32826 is not recommended for use in animal models.

Publications

1) Ferry, G., N. Moulharat, et al. (2008). “S32826, a nanomolar inhibitor of autotaxin: discovery, synthesis and applications as a pharmacological tool.” J Pharmacol Exp Ther 327(3): 809-19.
2) Conrotto, P., U. Andrasson, et al. (2011). “Knock-down of SOX11 induces autotaxin-dependent increase in proliferation in vitro and more aggressive tumors in vivo.” Molecular Oncology 5(6): 527.
3) Li, S., C. Xiong, et al. (2012). “ATX and LPA receptor 3 are coordinately up-regulated in lipopolysaccharide-stimulated THP-1 cells through PKR and SPK1-mediated pathways.” FEBS Letters 586(6): 792.

Categories

Biochemical Reagents

Filter

Autotaxin, Inhibitor

CAS Number

1103672-43-0

Molecular Formula

C21H34NNa2O4P

Molecular Weight (g/mol)

441.2

Purity

>98%

Storage

-20 °C or below

Shipping Temp

Gel Ice

Technical Data Sheet

You may also like…

  • PF-8380, ATX Inhibitor - Echelon Biosciences
    Biochemical Reagents

    PF-8380 (Autotaxin Inhibitor)

    Product Number: B-0702

    $54$195 View products
  • Autotaxin Inhibitor Screening Kit - Echelon Biosciences
    Kits & Assays

    Autotaxin Inhibitor Screening Kit

    Product Number: K-4200

    $537 View products
  • Antibodies & Proteins

    Autotaxin Enzyme, active

    Product Number: E-4000

    $106$501 View products
  • Autotaxin Activity Assay - Echelon Biosciences
    Kits & Assays

    Autotaxin Activity Assay

    Product Number: K-4100

    $563 View products
  • FS-3 (LysoPLD / Autotaxin fluorogenic substrate) - Echelon Biosciences
    Biochemical Reagents

    FS-3 (LysoPLD / Autotaxin substrate)

    Product Number: L-2000

    $363$2,927 View products
  • Kits & Assays

    Lysophosphatidic Acid ELISA Kit

    Product Number: K-2800S

    $969 View products
  • HA130 (Autotaxin Inhibitor) - Echelon Biosciences
    Biochemical Reagents

    HA130 (Autotaxin Inhibitor)

    Product Number: B-0701

    $67$126 View products
  • Autotaxin Sandwich ELISA Kit - Echelon Biosciences
    Kits & Assays

    Autotaxin Sandwich ELISA Kit

    Product Number: K-5600

    $626 View products
  • BrP-LPA (LPA bromophosphonate) - Echelon Biosciences
    Biochemical Reagents

    BrP-LPA

    Product Number: L-7416

    $160$719 View products
Shopping Cart
Scroll to Top

Technical Support

Bulk & Custom Orders