Purified Anti-PtdIns(3,4)P2 IgG

Product Number: Z-P034

$478
$1,756

Purified Anti-PtdIns(3,4)P2 antibody
Subtype: IgG3
Source: Mouse
Applications: ELISA, Immunofluorescence, Protein-Lipid Overlay


Phosphatidylinositol 3,4-bisphosphate (PI(3,4)P2) is produced in stimulated cells by the action of phosphatidylinositol 3-kinases (PI3Ks) and/or lipid phosphatases (SHIP, TPTE, etc.). PI(3,4)P2 binds the pleckstrin homology (PH)-domain of AKT/PKB leading to cell survival and it also has an important role in podosome formation near focal adhesions.

Storage

2-8 °C for up to 30 days, -20 °C for greater than 30 days. Do not freeze thaw multiple times.

Featured in Publications

1) Chiang, H. C., L. Wang, et al. (2010). “PI3 kinase signaling is involved in Abeta-induced memory loss in Drosophila.” Proc Natl Acad Sci U S A 107(15): 7060-5.


Technical Data Sheet

Categories

Antibodies & Proteins

Filter

Antibody, Lipid Binding, PI(3,4)P2

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