PTH Related Peptide [Leu11, DTrp12] (7-34) amide, human

Molecular Weight: 3479.11
Salt Form: TFA
Purity: >95%
Sequence (3-letter): Leu-Leu-His-Asp-Leu-DTrp-Lys-Ser-Ile-Gln-Asp-Leu-Arg-Arg-Arg-Phe-Phe-Leu-His-His-Leu-Ile-Ala-Glu-Ile-His-Thr-Ala-NH2
Sequence (1-letter): LLHDL(DTrp)KSIQDLRRRFFLHHLIAEIHTA-NH2
Storage: -20 °C or below

PTH Related Peptide [Leu11, DTrp12] (7-34) amide is a receptor PTH/PTHrP antagonist. Parathyroid hormone-related protein (PTHrP) is expressed in some human cancers (breast and certain lung cancers) but has normal functions in mammary gland development, tooth eruption, and fetal bone development. Tumor secretion of PThrP can lead to hypercalcemia which can be an initial indication of malignancy.