Molecular Weight: 3364.97
Salt Form: TFA
Sequence (3-letter): Leu-Leu-His-Asp-Lys-Gly-Lys-Ser-Ile-Gln-Asp-Leu-Arg-Arg-Arg-Phe-Phe-Leu-His-His-Leu-Ile-Ala-Glu-Ile-His-Thr-Ala-NH2
Sequence (1-letter): LLHDKGKSIQDLRRRFFLHHLIAEIHTA-NH2
Storage: -20 °C or below
PTH Related Peptide (7-34), aka PThrP (7-34), amide is a potent antagonist of the parathyroid hormone 1 receptor (PTH1R). Parathyroid hormone-related protein (PTHrP) is expressed in some human cancers (breast and certain lung cancers) but has normal functions in mammary gland development, tooth eruption, and fetal bone development. Tumor secretion of PThrP can lead to hypercalcemia which can be an initial indication of malignancy.