PI(4)P diC8

Phosphatidylinositol 4-phosphate diC8 (PI(4)P diC8) is a synthetic, purified dioctanoyl PI(4)P.

Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 4-phosphate (PI(4)P) is the biosynthetic precursor to PI(4,5)P2 and has an important roles in regulating sphingomyelin and glycosphingolipid metabolism and membrane trafficking at the exit of the Golgi complex.

Alternate names: D-myo-Phosphatidylinositol 4-phosphate, Dioctanoyl Phosphatidylinositol 4-phosphate, PtdIns(4)P C8,  PI(4)P C8, 8:0/8:0 PI(4)P

Bulk discounts available, please email echelon@echelon-inc.com for information.

Publications

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1) Chang, J. D., S. J. Field, et al. (2004). “Identification and characterization of a phosphoinositide phosphate kinase homolog.” J Biol Chem 279(12): 11672-9.
2) Redfern, D. A. and A. Gericke (2004). “Domain formation in phosphatidylinositol monophosphate/phosphatidylcholine mixed vesicles.” Biophys J 86(5): 2980-92.
3) Andersen, J. F. and J. M. C. Ribeiro (2006). “A Secreted Salivary Inositol Polyphosphate 5-Phosphatase from a Blood-Feeding Insect: Allosteric Activation by Soluble Phosphoinositides and Phosphatidylserine.” Biochemistry 45(17): 5450.